Thanks to ackermaniv and Neil for the following from Ausiello. I've taken out all the "fluff" and just left the spoilers in.
Update: 10:00 GMT Thanks to several of you, it looks like you might have cracked Ausiello's code, without the need for any Hangman style clues ;) Here are some of the better guesses so far.
New ones will be added at the top of the list below.
Someone who may be the daddy, but wasn't ever a father
someone who was on the plane, but wasn't near a window
Someone who got on the plane, but didn't have a choice
someone she met in her youth, who didn't have a mother
someone who was in the crash, but didn't have a kidney
someone who was in the crash, but didn't have a father
someone who was on the plane, but didn't want a rescue
someone she met in the hatch, but didn't call a friend
Someone she let be her lover, but hasn't been a friend
someone she met at the beach, who didn't have a mother
someone who was on the plane, but wasn't ever a Lostie
someone who was in the cabin, who wasn't just a shadow
someone who sat on the plane, who wasn't just a friend
Someone who was on the beach, but didn't want a rescue
someone who was in the hatch, but didn't push a button
someone who was on the plane, and Kate's also a mother
someone who was on the plane, but didn't have a ticket
someone she met in the hatch, but didn't call a coward
someone who may be her child, but didn't have a father
someone who was on the plane, but didn't need a collar
Someone she met in her trial, and Kate's also a mother
someone she met at her trial, who didn't need a lawyer
someone *** *** ** *** *****, *** ****'* **** a ******
They all look good to me! Vincent? One of the Crew/Pilot, a Stowaway, Locke, Sayid, was Kate pregnant before the crash? Speculate below and I'll post/update with any other good guesses.
Question: Can you tell us anything about what's going to happen with Jack and Kate on Lost this season? — Heinzy
Ausiello: Yes, but I have to be very careful how I dole out this particular spoiler, because it concerns a pretty jaw-dropping twist — even by Lost standards. Let's see… Jaters will be aflutter when Kate shows romantic interest in future Jack, but it turns out there's another special person in her life already — someone *** *** ** *** *****, *** ****'* **** a ******.
Question: Welcome back! If you're reading this, you must have survived the shooting. Phew! I was almost as worried about you as I was about the Lost Internet buzz. I'm hearing "death" "shocking twist" and "traitor." Does that mean Jack and Juliet won't have any time to make out? Got any Clues? Hints? Poop? — Amy
Ausiello: Unfortunately, I'm hearing there's nothing major going on in the Juliet-Jack universe in the first four episodes — unless you consider "heaps of subtext" to be major. (Hint: You may want to rewind to the Season 3 finale and figure out who initiated that smooch.)
Question: I just saw a preview that said "check out the two-hour Lost season premiere on Jan. 31, 2008." Does that mean they're sandwiching the first two episodes together? — Conor
Ausiello: Sure doesn't. The first episode will be preceded by an hour-long recap special, hence the "two-hour" premiere.
Source: TV Guide